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The center of any Sphere which has a contact of (at least) first-order with a curve  at a point
 at a point  lies
in the normal plane to
 lies
in the normal plane to  at
 at  .  The center of any Sphere which has a contact of (at least) second-order with
.  The center of any Sphere which has a contact of (at least) second-order with  at point
at point  , where the Curvature
, where the Curvature  , lies on the polar axis of
, lies on the polar axis of  corresponding to
 corresponding to  .  All these
Spheres intersect the Osculating Plane of
.  All these
Spheres intersect the Osculating Plane of  at
 at  along a circle of curvature at
 along a circle of curvature at  .  
The osculating sphere has center
.  
The osculating sphere has center
 
 is the unit Normal Vector,
 is the unit Normal Vector,  is the unit Binormal Vector,
 is the unit Binormal Vector,  is the
Radius of Curvature, and
 is the
Radius of Curvature, and  is the Torsion, and Radius
 is the Torsion, and Radius
 
 .
.
See also Curvature, Osculating Plane, Radius of Curvature, Sphere, Torsion (Differential Geometry)
References
Kreyszig, E.  Differential Geometry.  New York: Dover, pp. 54-55, 1991.